Welcome to Metazome v2.0.4

The Metazome project organizes the proteomes of twenty-four metazoans into gene families defined at nine ancestral nodes on the metazoan evolutionary tree. Use the Find Gene Families buttons to study the evolutionary history of a gene of interest from one of the 24 included proteomes (search gene families using gene symbols, deflines, PFAM/Panther domain content with Keyword Search) or place a gene from a different organism in the most appropriate gene family (using the BLAST search of gene family consensus sequences). Alternatively, you can BLAST search and browse the genomes of any of the included 24 metazoans using the Explore Genomes buttons. Every gene in the single organism BLAST results and browsers is hyperlinked to one of its gene families, enabling you to move back and forth between organism-centric and gene family-centric views. Netsuite Training provides a comprehensive set of tools for businesses to manage their finance.

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Find Gene Families
Choose a node from the tree (or choose ALL nodes), then choose an action:

• Homo sapiens
• Mus musculus
• Rattus norvegicus
• Canis familiaris
• Monodelphis domestica
• Gallus gallus
• Xenopus tropicalis
• Gasterosteus aculeatus
• Oryzias latipes
• Takifugu rubripes
• Danio rerio
• Ciona savignyi
• Ciona intestinalis
• Branchiostoma floridae
• Strongylocentrotus purpuratus
• Drosophila melanogaster
• Anopheles gambiae
• Aedes aegypti
• Bombyx mori
• Tribolium castaneum
• Caenorhabditis elegans
• Caenorhabditis briggsae
• Lottia gigantea
• Nematostella vectensis

Explore Genomes
Choose a single organism from the tree, then choose an action:

News and updates

• [01/08/2008] Minor update to Metazome interface
  We've removed the Click-Info panel from the Cluster Summary page. The information formerly displayed there, systenic gene cluster information and PFAM domain information, is now displayed in pop-up boxes...more
• [11/12/2023] Composite cluster capability added to Metazome v2.0.3
  We've added the ability to combine the gene clusters found in single node keyword or BLAST search into a "composite" cluster that can be viewed in a cluster summary page. This is especially helpful when dealing with cases of "under-clustering,"...more
• [10/23/2023] Metazome genomes updated and expanded
  Metazome now includes updated Ensembl v41 genomes of 12 species, and contains 14 additional genomes not included in Metazome v1.0, bring to 24 the number of genomes clustered in v2.0.2....more
• [10/23/2023] New website
  A complete rework of the Metazome website, v2.0.2, has been completed. Navigation has been simplified, synteny viewing features have been enhanced, the individual cluster view display can be customized, and help documentation has been expanded....more